Tag archives for Tuberculosis

Tuberculosis with Eosinophilic Mass and Dark Brown Particles

Delyuzar1, M. Najib Dahlan Lubis1, Zainuddin Amir2, Lia Kusumawati3 1Departemen Patologi Anatomik, Fakultas Kedokteran Universitas Sumatera Utara, Medan 2Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Sumatera Utara, Medan 3Departemen Mikrobiologi, Fakultas Kedokteran Universitas Sumatera Utara, Medan Abstract Background: Sputum smear examination and X-ray images have been used to identify pulmonary tuberculosis patients. For extrapulmonary […]

Evidence Based Medicine Case Report: Two Times Acid Fast Bacilli (AFB) Sputum Examination VS Three Times AFB Sputum Examination in The Diagnosis of Pulmonary Tuberculosis

Kolanda Maria, Jaswin Dhillon, Linda Apriel Rolobessy, Mulkan Azhary, Vebiyanti Tentua, RR Diah Handayani, Jamal Zaini Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Diagnosis of active pulmonary tuberculosis (TB) still rely on the acid-fast bacilli (AFB) sputum smear. Pulmonary TB with three times sputum smear sometimes difficult to obtain […]

Factors Affecting Sputum Conversion in New Cases of Pulmonary Tuberculosis Patients New Cases with Diabetes Mellitus

Iceu Dimas Kulsum,1 Erlina Burhan,1 Rochismandoko2 1Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta 2Departemen Ilmu Penyakit Dalam, RSUP Persahabatan, Jakarta Abstract Background: The prevalence of diabetes mellitus (DM) continues to increase in developing countries where TB is endemic. Immunocompromised due to DM increases the risk of TB infection and delayed […]

Accuracy of Urine LAM TB Antigen Test as an Alternative Method of Pulmonary Tuberculosis Diagnosis; Evidence-based Case Report

Hafizh A Boenjamin,1 Ikrar Syahmar,1 Joseph Prasetyo,1Nadim Marchian,1 Theresia Rini,1 Jamal Zaini2 1Program Pendidikan Dokter Fakultas Kedokteran Universitas Indonesia 2Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Tuberculosis (TB) cases are found in many developing countries, such as Indonesia. The diagnosis of TB still depends on microscopic examination of sputum […]

Conversion Failure at The End of DOTS Intensive Phase among Acid Fast Bacilli Positive Pulmonary Tuberculosis

Reny Setiowati,1 Dumilah Ayuningtyas2 1Rumah Sakit Umum Banten 2Departemen Administrasi Kebijakan Kesehatan Fakultas Kesehatan Masyarakat Universitas Indonesia Abstract Background: Indonesia ranks ninth out of twenty-seven countries which has the burden of multi drug resistance (MDR) tuberculosis (TB) in the world. The failure of conversion in TB patients was one of the contributing factor to anti […]

Smoking Effect to Sputum Conversion of Pulmonary Tuberculosis Patients Category I

Masdewi Wahyuni,1 Zainuddin Amir,2 Rina Yunita,3 Widi Rahardjo,2 Alwinsyah Abidin4 1Ilmu Kedokteran Tropis, Fakultas Kedokteran Universitas Sumatera Utara 2Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sumatera Utara, RSUP Haji Adam Malik, Medan 3Departemen Mikrobiologi, Fakultas Kedokteran Universitas Sumatera Utara, RSUP Haji Adam Malik Medan, 4Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran Universitas Sumatera Utara, RSUP […]

Combating Tuberculosis in Disaster Affected Areas: Lesson Learnt from Multidrug Resistant Tuberculosis Phenomenon after 8 Years of Tsunami in Aceh

Tristia Rinanda,1 Mulyadi2 1Bagian Mikrobiologi, Fakultas Kedokteran Universitas Syiah Kuala 2Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Syiah Kuala Abstract The tsunami on December 26, 2004 has provided a tremendous impact for the people of Aceh. One of the real impacts of the disaster was an increase in mortality and morbidity of infectious diseases, […]

Interleukin-10-1082G/A Gene Polymorphism as a Potential Host Susceptibility Factor in Patients with Multidrug Resistant Tuberculosis

Novita Eva Sawitri,1 Reviono,1 Suradi,1 Afiono Agung Prasetyo2 1Bagian Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta 2Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Sebelas Maret, Surakarta Abstract Background: This study was conducted to determine the association between polymorphism of interleukin (IL)-10 -1082G/A gene on susceptibility of multidrug resistant tuberculosis (MDR-TB). Polymorphism […]

Comparison Acid Fast Bacilli Smear Microscopy Examination with Xpert MTB/RIF in Diabetes Mellitus Patients Who Suspected Pulmonary Tuberculosis

Sukara Safril Kusuma Jaya¹, Erlina Burhan¹, Rochsismandoko², Cahyarini³ ¹Departemen Pulmonologi dan Ilmu Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RS Persahabatan, Jakarta ²SMF Penyakit Dalam, Divisi Metabolik dan Endokrin, RS Persahabatan, Jakarta ³SMF Mikrobiologi, RS Persahabatan, Jakarta Abstract Background: The relationship between tuberculosis (TB) and Diabetes Mellitus (DM) has long been known. People with DM have […]

Pulmonary Tuberculosis in Patients with Diabetes Mellitus Type 2

Agung Wijayanto¹, Erlina Burhan¹, Arifin Nawas¹, Rochsismandoko² ¹Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RS Persahabatan, Jakarta ²Departemen Ilmu Penyakit Dalam, RS Persahabatan, Jakarta Abstract Background: Diabetes mellitus (DM) is estimated to be 366 million by 2030, with the fastest increase in low and middle income countries. Approximately one-third of the world […]

Relations beetwen Social Capital and Tuberculosis Case Detection Rate Achievement of Health Care Centre in Karanganyar Regency

Reviono, Suradi, Mulyono Adji, Endang Sutisna Sulaeman Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Sebelas Maret Abstract Background: Karanganyar regency never reached the national target of tuberculosis case detection rate (CDR) of 70%. Social capital is social ties and strength of individuals in the community to achieve common goals. The objective is to […]

An Association between Vitamin D levels in Blood and Pulmonary Tuberculosis Cases

Jon Pangarapan Saragih, Bintang Sinaga, Zainuddin Amir Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Sumatera Utara, RSUP H. Adam Malik, Medan Abstract Background: Vitamin D is known to have an important role in macrophage activation and the subsequent restriction of Mycobacterium tuberculosis growth, and it has been implicated as a risk factor for […]

Correlation between Tuberculosis Sequelae with 6 Minute Walking Test in Patients with Pulmonary Tuberculosis Sequelae

Azzaky, Bambang Sigit Riyanto, IkaTrisnawati, Barmawi Hisyam, Sumardi, Eko Budiono, Heni Retnowulan Sub Bagian Penyakit Paru Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Gajah Mada, RSUP Dr. Sardjito, Yogyakarta Abstract Background: Tuberculosis (TB) often result in diffuse fibrosis in the lung tissue, resulting in decreased lung function as a whole. Functional walking test, for example the six minute walking test […]

Streptomycin and Incidence of Hearing Loss in Multidrug Resistant Tuberculosis Patients in Dr. Moewardi Hospital

Reviono, Widayanto, Harsini, Jatu Aphridasari, Yusup Subagio Sutanto Abstract Background: Multidrug resistant tuberculosis (MDR TB) is known as threatening and challenging community health problem worldwide. Treatment of MDR TB is difficult because it needs higher cost, longer treatment period, and more adverse events than drug-sensitive TB. Hearing loss is a major adverse event due to […]

Characteristics and Evaluations of Illness of Multidrug Resistant Tuberculosis With and Without Diabetes Mellitus

Risky Akaputra, Erlina Burhan, Arifin Nawas Abstract Background : Approximately 500.000 new cases of multidrug resistant tuberculosis (MDR TB) in the worldwide. One study found diabetes mellitus (DM) as a contributing factor to develop MDR TB. Diabetes mellitus is known as risk factor to reactivation, late conversion and more complication during tuberculosis treatment. In this […]

Comparison of Clinical, Radiological Finding and Culture Conversion of Diabetic and Non Diabetic Multidrug Resistant Tuberculosis Patients in Dr. Moewardi Hospital

Reviono, Indah Juliana, Harsini, Jatu Aphridasari, Yusup Subagio Sutanto Abstract Background : Diabetes mellitus (DM) is a risk factor for tuberculosis and may modify its presenting features. There is good evidence that DM makes a substansial contribution to TB incidence. Considering the contradictory results of the previous studies, this study was conducted for further investigation, […]

Surgery in Extensively Drug Resistant Tuberculosis, Emphasized in the Preventing of Disease Transmision to the Environment: Case Study in Persahabatan Hospital

Panji Utomo, Susan Hendriarini Mety, Agung Wibawanto Abstract The burden of tuberculosis in Indonesia has become more emerging and challenging with the increasing number of multidrug resistant tuberculosis (MDR TB) and the extensively drug resistant tuberculosis (XDR TB). The XDR TB is defined as resistance to at least rifampicin and isoniazid (which is the definition […]

Diabetes Mellitus and Its Problems in Tuberculosis Infection

Dyah Retno Wulandari, Yani Jane Sugiri Abstract Diabetes mellitus (DM) increases the risk of active tuberculosis (TB) infection by 3.11 times. With the increase in the pandemic, which 80% DM in TB endemic areas, the TB will be a problem in the future. Although the incidence rate of TB has decreased, but still not reached […]

Diagnosing Tuberculosis using ESAT-6 and CFP-10 Antigen Complex

Irandi Putra Pratomo, Darmawan Budi Setyanto Abstract The challenge of tuberculosis (TB) remains in diagnosing the disease particularly in the young age group children. Clinical manifestations of TB in children are usually subtle and are not similar to the adult counterpart because of the pathogenesis of TB itself. The paucibacillary phase, which is common in […]

Primary Resistance in Category I of Pulmonary Tuberculosis Patients at Adam Malik Hospital, Medan

Hendra Sihombing, Hilaluddin Sembiring, Zainuddin Amir, Bintang Y.M. Sinaga. Abstract Background: The resistance case is a problem for TB prevention and eradication programme in the world. Therefore, it is important to investigate the rate and the pattern of primary resistance in pulmonary tuberculosis. The aim of this study was to evaluate the incidence and pattern […]

Peroxidative Index Model and Advanced Oxidation Protein Products Level of Pulmonary Tuberculosis Patients Saliva Based on Length of Treatment

Setiawan B, Adenan, Suhartono E. J Respir Indones. 2012;32(2):72-7. Abstract Introduction: Mycobacterium tuberculosis in human induce variety response involved protective immunity to clinical manifestation of tuberculosis. Oxidative mechanism to infection controlling not only happened in macrofag but in all liquid compartment of body. Methods: Aim of this study was to evaluate peroxidative index and advanced […]

Factors Affecting Treatment Failure of Tuberculosis Empyema with Chest Tube Drainage at Persahabatan Hospital

Yovi I, Swidarmoko B, Burhan E. J Respir Indones. 2012;32(2):78-84. Abstract: Introduction: The therapy for tuberculosis empyema is more complicated compared to the therapy for non-tuberculosis empyema. Surgical treatment is frequently necessary. However, the optimum time at which surgical intervention must be performed is still not settled. Methods: The medical records of patients with final […]

Tuberculosis – HIV Coinfection Profile in Dr. Moewardi Hospital Surakarta Year 2010-2011

Surjanto E, Sutanto YS, Reviono, Harsini, Marsabessy QL. J Respir Indones. 2012;32(2):85-8. Abstract Introduction: Tuberculosis is the commonest opportunistic infection in human immunodefisiency virus (HIV) patients. Aim this study was to describe TB-HIV coinfection patients among TB patients according to clinical symptoms, acid fast bacili, chest radiography. Methods: Descriptive study from medical record of 37 […]

Sensitivity and Specificity of Mycobacteria Tuberculosis Culture Using Liquid Media on Bronchoalveolar Lavage From Negative Acid Fast Bacili Pulmonary Tuberculosis Patients

Setiarsih HS, Wiyono WH, Burhan E, Soemanto RK, Widyahening IS. J Respir Indones. 2012;32(2):89-99. Abstract: Introduction: Diagnostic tuberculosis using acid fast bacilli (AFB) microscopy and conventional Lowenstein Jensen (LJ) culture remain the cornerstone but the sensitivity of these traditional methods is quite low, especially in the samples containing small number of organism. There is a […]

Diagnosis dan Penatalaksanaan Mycobacterium Other than Tuberculosis (MOTT)

Restiawati NM, Burhan E. J Respir Indones. 2011;31(3):156-64. Mycobacterium other than tuberculosis (MOTT) diisolasi pertama kali tahun 1885 segera setelah ditemukan Mycobacterium tuberculosis dan baru dianggap sebagai kuman patogen pada manusia sekitar tahun 1950-an. Genus Mycobacterium termasuk famili Mycobateriaceae dan merupakan ordo Actynomycetales, serta memiliki lebih dari 125 spesies kecuali M. tuberculosis dan M. leprae […]