Tag archives for MDR

Interleukin-10-1082G/A Gene Polymorphism as a Potential Host Susceptibility Factor in Patients with Multidrug Resistant Tuberculosis

Novita Eva Sawitri,1 Reviono,1 Suradi,1 Afiono Agung Prasetyo2 1Bagian Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta 2Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Sebelas Maret, Surakarta Abstract Background: This study was conducted to determine the association between polymorphism of interleukin (IL)-10 -1082G/A gene on susceptibility of multidrug resistant tuberculosis (MDR-TB). Polymorphism […]

Streptomycin and Incidence of Hearing Loss in Multidrug Resistant Tuberculosis Patients in Dr. Moewardi Hospital

Reviono, Widayanto, Harsini, Jatu Aphridasari, Yusup Subagio Sutanto Abstract Background: Multidrug resistant tuberculosis (MDR TB) is known as threatening and challenging community health problem worldwide. Treatment of MDR TB is difficult because it needs higher cost, longer treatment period, and more adverse events than drug-sensitive TB. Hearing loss is a major adverse event due to […]

Characteristics and Evaluations of Illness of Multidrug Resistant Tuberculosis With and Without Diabetes Mellitus

Risky Akaputra, Erlina Burhan, Arifin Nawas Abstract Background : Approximately 500.000 new cases of multidrug resistant tuberculosis (MDR TB) in the worldwide. One study found diabetes mellitus (DM) as a contributing factor to develop MDR TB. Diabetes mellitus is known as risk factor to reactivation, late conversion and more complication during tuberculosis treatment. In this […]

Comparison of Clinical, Radiological Finding and Culture Conversion of Diabetic and Non Diabetic Multidrug Resistant Tuberculosis Patients in Dr. Moewardi Hospital

Reviono, Indah Juliana, Harsini, Jatu Aphridasari, Yusup Subagio Sutanto Abstract Background : Diabetes mellitus (DM) is a risk factor for tuberculosis and may modify its presenting features. There is good evidence that DM makes a substansial contribution to TB incidence. Considering the contradictory results of the previous studies, this study was conducted for further investigation, […]

Surgery in Extensively Drug Resistant Tuberculosis, Emphasized in the Preventing of Disease Transmision to the Environment: Case Study in Persahabatan Hospital

Panji Utomo, Susan Hendriarini Mety, Agung Wibawanto Abstract The burden of tuberculosis in Indonesia has become more emerging and challenging with the increasing number of multidrug resistant tuberculosis (MDR TB) and the extensively drug resistant tuberculosis (XDR TB). The XDR TB is defined as resistance to at least rifampicin and isoniazid (which is the definition […]

Editorial : Multi-Drug Resistance (MDR) pada Tuberkulosis

Sutoyo DK. J Respir Indones. 2010;30(2):72-74. Resistensi obat pada Tuberkulosis (TB) menjadi kesulitan utama pada pengobatan TB. Hal yang ditakutkan pada pengobatan TB adalah jika telah terjadi resistensi obat apalagi resisten terhadap banyak obat anti tuberkulosis lini pertama (poliresisten). Rifampisin (R) dan Isoniazid (H) adalah tulang punggung rejimen pengobatan karena kombinasi kedua obat tersebut mempunyai […]

Pengamatan Pasien Tuberkulosis Paru dengan Multi-drug Resistant (TB-MDR) di Poliklinik Paru RSUP Persahabatan

Munir SM, Nawas A, Sutoyo DK. J Respir Indones. 2010;30(2);92-104. Background : Multi-drug resistant with pulmonary tuberculosis (MDR-TB) incidence rise to 2% every year, mean while the prevalence of MDR-TB in the world is 4.3%. the pattern of MDR-TB in Indonesia especially at Persahabatan hospital in 1995-1997 are; Primary resistant 4.6%-5.8% and Secondary resistant 22.95% […]