Diabetes Mellitus and Its Problems in Tuberculosis Infection

· Lung Infection

Dyah Retno Wulandari, Yani Jane Sugiri

Diabetes mellitus (DM) increases the risk of active tuberculosis (TB) infection by 3.11 times. With the increase in the pandemic, which 80% DM in TB endemic areas, the TB will be a problem in the future. Although the incidence rate of TB has decreased, but still not reached a trend that is expected to reach the target rate of incidence to 1 new case per 1 million populations. Diabetes is a disease with immune system disorders, especially the impact of cellular immune system where the system is the critically role of the restriction of TB infection. Diabetes manifestation impact of TB is worse than TB patients without DM. Diabetes can be a risk factor of bacterial load in the sputum smear, with a longer conversion then TB patients without DM, thereby increasing the risk of transmission and the risk of bacterial resistance. Diabetes also affects the prognosis in the treatment of TB. It can increase mortality, the risk of treatment failure and relapse. Guidelines for care and control of TB with DM has not been supported by comprehensive research. WHO began pioneering the guideline in care and control since 2009. WHO guidelines in 2011 remains a global guide and benchmark the development of further research. (J Respir Indo. 2013; 33:126-34)

Click for details

Leave a Comment