Triwahju Astuti,1 Tri Yudani Mardining Raras,2 Dian Nugrahenny,3 Rahadi Widodo1 1Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Brawijaya, Malang 2Laboratorium Biomedik, Fakultas Kedokteran Universitas Brawijaya, Malang 3Laboratorium Farmakologi, Fakultas Kedokteran Universitas Brawijaya, Malang Abstract Background: In suspected MDR-TB patients with smear AFB remains positive after treatment, the results of mycobacterial culture are not always […]
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Novita Eva Sawitri,1 Reviono,1 Suradi,1 Afiono Agung Prasetyo2 1Bagian Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta 2Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Sebelas Maret, Surakarta Abstract Background: This study was conducted to determine the association between polymorphism of interleukin (IL)-10 -1082G/A gene on susceptibility of multidrug resistant tuberculosis (MDR-TB). Polymorphism […]
Tamam Anugrah Tamsil, Arifin Nawas, Dianiati Kusumo Sutoyo Abstract MDR-TB is a major public health concern in several countries. The results of PMDT have not been impressive with the proportion of successfully treated MDR-TB patients in most countries below 60% and the proportion of loss to follow-up and failure were high. Recommended treatment regimens are very long, […]
Bintang Yinke Magdalena Sinaga Abstract Background : Multidrug resistant tuberculosis (MDR TB) is a problem for TB prevention and eradication. Programmatic management of drug-resistant TB (PMDT) is a program for MDR TB. The objective of this study was to evaluate the proportion and characteristic of MDR TB patients at PMDT programme in Adam Malik Hospital, Medan, Indonesia. Methods […]
Reviono, Widayanto, Harsini, Jatu Aphridasari, Yusup Subagio Sutanto Abstract Background: Multidrug resistant tuberculosis (MDR TB) is known as threatening and challenging community health problem worldwide. Treatment of MDR TB is difficult because it needs higher cost, longer treatment period, and more adverse events than drug-sensitive TB. Hearing loss is a major adverse event due to […]
Risky Akaputra, Erlina Burhan, Arifin Nawas Abstract Background : Approximately 500.000 new cases of multidrug resistant tuberculosis (MDR TB) in the worldwide. One study found diabetes mellitus (DM) as a contributing factor to develop MDR TB. Diabetes mellitus is known as risk factor to reactivation, late conversion and more complication during tuberculosis treatment. In this […]
Panji Utomo, Susan Hendriarini Mety, Agung Wibawanto Abstract The burden of tuberculosis in Indonesia has become more emerging and challenging with the increasing number of multidrug resistant tuberculosis (MDR TB) and the extensively drug resistant tuberculosis (XDR TB). The XDR TB is defined as resistance to at least rifampicin and isoniazid (which is the definition […]
Munir SM, Nawas A, Sutoyo DK. J Respir Indones. 2010;30(2);92-104. Background : Multi-drug resistant with pulmonary tuberculosis (MDR-TB) incidence rise to 2% every year, mean while the prevalence of MDR-TB in the world is 4.3%. the pattern of MDR-TB in Indonesia especially at Persahabatan hospital in 1995-1997 are; Primary resistant 4.6%-5.8% and Secondary resistant 22.95% […]