Dicki Harnanda Prihandono, Suradi Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta Abstract Background: Inspiratory muscle execises is a pulmonary rehabilitation methods in patients with chronic obstructive pulmonary disease (COPD) that relatively new and highly developed Research on muscle exercises is very varied and not yet adjustable. This study […]
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Andi Wijayanto, Susanthy Djajalaksana, Teguh R Sartono, Harun Al Rasyid Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Brawijaya, Malang Abstract Background: One of the main problems in patients with COPD is muscle wasting which is a significant decline in the structure and function of skeletal muscle. The purpose of this study is to look […]
Triwahju Astuti, Ungky Agus Setyawan, Sri Handayani Rahayu Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Brawijaya, Malang Abstract Background: In chronic obstructive pulmonary disease (COPD,) especially in smoker patients, there is a reduction in histone deacetylase-2 (HDAC2) activity and expression which is caused by oxidative stress. It’s linked with corticosteroids resistance. GOLD recommendation therapy […]
Nurfitriani Usman,1 Faisal Yunus,1 Tribowo Tuahta Ginting2 1Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta 2Departemen Ilmu Kedokteran Jiwa, Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Background: Patients with COPD typically elderly, have comorbid diseases and their significant relations with their smoking history. One of the most frequent comorbid in […]
Indah Juliana, Suradi, Ana Rima Setijadi Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret, RSUD Dr. Moewardi, Surakarta Abstract Background: Inflammation of COPD is persistent and progressive. Chronic inhalation of cigarette smoke causes the neutrophil infiltration into the airways, release cytokines, proinflammatory chemokines and proteases, especially MMP-9. Structural abnormalities lead to hyperinflation and […]
Budi Yanti,1 Menaldi Rasmin2 1SMF Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Syiah Kuala, RSUD Dr. Zainoel Abidin, Banda Aceh 2 Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Theophylline has been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD) for over 60 years and remains […]
Ratih Pahlesia,1 Faisal Yunus,1 Budhi Antariksa,1 Ratnawati,1 Dody Widodo1 1Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta 2Departemen THT Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Background: Patients with COPD may have a concomitant sleep apnea that can further exacerbate their gas exchange during sleep. They have an increased risk […]
Danar Pratama Putra, Nurfitri Bustamam, Aulia Chairani Fakultas Kedokteran Universitas Pembangunan Nasional Veteran, Jakarta Abstract Background: Smoking is responsible for approximately 90% of COPD. Smoking cessation is one of nonpharmacological managements for COPD patient. This study was aimed to determine the relationship between smoking cessation and the severity of COPD based on GOLD 2013. Methods: […]
Iceu Dimas Kulsum, Faisal Yunus Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta Abstract Metabolic syndrome is a complex disorder and an emerging clinical challenge, recognized clinically by the findings of abdominal obesity, elevated triglycerides, atherogenic dyslipidemia, elevated blood pressure, high blood glucose and/or insulin resistance. Metabolic syndrome is 1.5-3 times […]
Dewi Kartikaningsih, Susanthy Djajalaksana, Moch. Ridwan, Harun Al Rasyid Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Brawijaya, Malang Departemen Ilmu Kedokteran Fisik dan Rehabilitasi, Fakultas Kedokteran Universitas Brawijaya, Malang Departemen Ilmu Kesehatan Masyarakat, Fakultas Kedokteran Universitas Brawijaya, Malang Abstract Background: Depression is a major comorbid for COPD patients and associated with decline in health […]
Dewi Manihuruk, Pandiaman Pandia, Amira Tarigan, Putri Chairani Eyanoer Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sumatera Utara, RSUP H. Adam Malik Medan Abstract Background: COPD is considered as a complex disease and global problem that is predicted to be the third most common cause of death by 2030. The 2014 GOLD (Global Strategy for […]
Zakiah Novianti¹, Suradi¹, Muchsin Doewes² ¹Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Sebelas Maret ²Departemen Kedokteran Olahraga, Fakultas Kedokteran Universitas Sebelas Maret Abstract Backgound: Exercise intolerance is one of the main factors limiting participation in activities of daily living among individuals with chronic obstructive pulmonary disease (COPD). Depletion of fat-free mass (FFM) significantly contributes […]
Ruri Intania, Taufik, Yusrizal Chan, Irvan Medison Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, RSUP Dr. M. Djamil, Padang Abstract Background: Lung damage facilitates the colonization of pathogenic bacteria in lower respiratory tract of COPD patients that induces inflammation of which indeed exacerbation, thus contributing to the progression of obstruction which is […]
Hendri Nofa, Yusrizal Chan, Masrul Basyar, Oea Khairsyaf Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, RSUP Dr. M. Djamil, Padang Abstract Background: Azithromycin is a macrolide, that have antibiotic anti inflammation property that might decrease progresivity of chronic obstructive pulmonary disease (COPD). CAT is a simple questionnaire, useful and sensitive for the […]
Meli Yusanti, Yusrizal Chan, Masrul Basyar, Yessy Susanty Sabri Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, Rumah Sakit Umum Pusat M.Djamil, Padang Abstract Background: COPD is a progressive respiratory disease with chronic inflammatory of the airway frequently accompanied by extra pulmonary symptoms. C reactive protein was one of the inflammatory marker with […]
Yeni Putri, Taufik, Yusrizal Chan, Irvan Medison Departemen Pulmonologi dan Ilmu Kedokteran Respirasi Fakultas Kedokteran Universitas Andalas, Rumah Sakit Umum Pusat M. Djamil, Padang Abstract Backgrounds: Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammation of the airway that is persistent and progressive. Patient with stable COPD frequently have bacterial colonization in lower respiratory tract […]
Jenny Wailan Kandowangko, Susanthy Djajalaksana, Harun Al Rasyid Abstract Background: Depression is a main comorbid in COPD and it is related with the decrease in health status and worse prognosis. There is also increase of abnormal inflammatory cells activation and increase of cytokine IL-6 during depression period. Methods: Observational cross sectional study, 36 stable COPD […]
Ferry Dwi Kurniawan, Prasenohadi, Faisal Yunus Abstract Chronic Obstructive Pulmonary Disease (COPD) exacerbation related to an increased risk of mortality, morbidity and health cost. Evidently, non invasive ventilation (NIV) has a role in reducing risk of in-hospital mortality, intubation and length of stay. By providing Positive End Expiratory Pressure (PEEP) extrinsically, it could overcome the […]
Aghnia Permatasari, Dita Gemiana, Fitriana Nur, Raditya Ardi, Wahyu Permatasari, Jamal Zaini Abstract Background: Chronic obstructive pulmonary disease (COPD) diagnosis using spirometry in primary care is quite difficult due to the availability. The aim of this study is to evaluate diagnosis value of symptom-based questionnaire in COPD diagnosis. Methods: Literature search using Pubmed, SCOPUS, and EBSCO databases […]
Mufidatun Hasanah, Susanthy Djajalaksana Abstract COPD is a complex syndrome with numerous pulmonary and extrapulmonary components with significant heterogeneity. The term phenotype in the field of COPD is defined as “a single or combination of disease attributes that describe differences between individuals with COPD as they relate to clinically meaningful outcomes”. Among all phenotypes identified, there are […]
Anwar D, Chan Y, Basyar M. J Respir Indo. 2012;32(4):200-7. Abstract Background: Although spirometry should be undertaken in all patients who may have COPD, in many areas practitioners lack access to spirometry. MMRC scale questionnaire can be used to assess the breathlessness. The aim of this study was determine the association between the degree of […]
Fachri M, Yunus F, Wiyono WH, Kekalih A. J Respir Indo.2012;32(4):208-17. Abstract Introduction: There is a correlation between the disturbance of endocrine glands and muscular weakness in COPD patients. Two hormones assumed to be affected are growth hormone and testosterone hormone. Methods: In observational case control study, we collected data consecutively from stable COPD patients […]
Suradi, Sutanto YS, Reviono, Harsini, Marhendra D. J Respir Indo.2012;32(4):218-22. Abstract Background: Respiratory tract infections are the leading cause of acute exacerbation of COPD (AECOPD). The aim of this study was to investigate the frequency of bacterial infection, bacterial profile, antibiotics sensitivity and comparison of patient characteristics according to sputum culture. Methods: A cross sectional […]
Sholikhah S, Yunus F, Wiyono WH. J Respir Indo.2012;32(4):223-32 Abstract Background: There is a correlation between elastin and pathogenesis of COPD in COPD patients. Desmosine is intermolecular and intramolecular cross link between the chains of elastin polypeptide. Elastin is the main component of lung connective tissue that maintains the elasticity of the lung. If there […]
Suwarti SA, Chan Y, Zainoeddin ZY, Taufik, Khairsyaf O J Respir Indo. 2012;32:233-9 Abstract Background: Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease with airflow limitation that is not fully reversible. Tobacco smoke and air pollution can cause oxidative stress which contribute in cell and tissue damage. N-Acetylcysteine is an antioxidant that […]