Archives for October, 2012

Editorial: Chronic Obstructive Pulmonary Disease (COPD): “GOLD Revised 2011” lebih aplikatif?

Djajalaksana S. J Respir Indo. 2012;32(4):198-9. Chronic obstructive pulmonary disease (COPD) atau disosialisasikan dengan bahasa Indonesia PPOK (penyakit paru obstruktif kronik) adalah penyakit paru yang dapat dicegah dan diobati, ditandai dengan limitasi aliran udara yang persisten dan progresif, akibat respons inflamasi kronik pada jalan  napas dan parenkim paru yang disebabkan gas atau partikel beracun. Eksaserbasi dan komorbid berkontribusi pada beratnya penyakit […]

Correlation Between The Degree of Breathlessness According to Modified Medical Research Council Scale (MMRC scale) with The Degree of Chronic Obstructive Pulmonary Disease

Anwar D, Chan Y, Basyar M. J Respir Indo. 2012;32(4):200-7. Abstract Background: Although spirometry should be undertaken in all patients who may have COPD, in many areas practitioners lack access to spirometry. MMRC scale questionnaire can be used to assess the breathlessness. The aim of this study was determine the association between the degree of […]

Comparison of Serum Testosterone and Growth Hormone in Stable Chronic Obstructive Pulmonary Disease Patients

Fachri M, Yunus F, Wiyono WH, Kekalih A. J Respir Indo.2012;32(4):208-17. Abstract Introduction: There is a correlation between the disturbance of endocrine glands and muscular weakness in COPD patients. Two hormones assumed to be affected are growth hormone and testosterone hormone. Methods: In observational case control study, we collected data consecutively from stable COPD patients […]

Characteristics of Acute Exacerbation COPD in Relation to Bacterial Sputum Culture Result at Dr. Moewardi Hospital Surakarta

Suradi, Sutanto YS, Reviono, Harsini, Marhendra D. J Respir Indo.2012;32(4):218-22. Abstract Background: Respiratory tract infections are the leading cause of acute exacerbation of COPD (AECOPD). The aim of this study was to investigate the frequency of bacterial infection, bacterial profile, antibiotics sensitivity and comparison of patient characteristics according to sputum culture. Methods: A cross sectional […]

Serum Desmosine Level in Stable Chronic Obstructive Pulmonary Diseases

Sholikhah S, Yunus F, Wiyono WH. J Respir Indo.2012;32(4):223-32 Abstract Background: There is a correlation between elastin and pathogenesis of COPD in COPD patients. Desmosine is intermolecular and intramolecular cross link between the chains of elastin polypeptide. Elastin is the main component of lung connective tissue that maintains the elasticity of the lung. If there […]

Effect of N-Acetyl Cysteine on Stable Chronic Obstructive Pulmonary Disease among Outpatients in Pulmonary Clinic in Dr. M. Djamil Hospital Padang

Suwarti SA, Chan Y, Zainoeddin ZY, Taufik, Khairsyaf O J Respir Indo. 2012;32:233-9 Abstract Background: Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease with airflow limitation that is not fully reversible. Tobacco smoke and air pollution can cause oxidative stress which contribute in cell and tissue damage. N-Acetylcysteine is an antioxidant that […]

Correlation of Sputum Macrophage and Neutrophil with COPD Assessment Test (CAT)

Wijaya o, Sartono TR, Djajalaksana S, Maharani A J Respir Indo.2012; 32(4):240-9 Abstract Introduction: The abnormality of COPD is caused by long standing inflammatory response, imbalance of proteinases and anti proteinases and increased oxidative stress in the airway. Increased airway inflammation will accelerate the decline in lung function and impair quality of life. This study […]

Ultra-Long Acting B2 Agonist (LABA) : Indacaterol for Chronic Obstructive Pulmonary Disease (COPD)

Amin M J Respir 1Indo. 2012; 32(4):250-4 Abstract Chronic Obstructive Pulmonary Disease (COPD) is characterised by progressive airflow limitation. According to Global Initiative forChronic Obstructive Lung Disease (GOLD), bronchodilators are the mainstay of therapy. The role of LABAs in the treatment of stable COPD, including bronchodilation and reduced air trapping resulting in improved lung function […]