Prevalence of Obstructive Sleep Apnea (OSA) in Patients with Mild to Severe COPD Based on Berlin Questionnaire and Polysomnography

· COPD, Lung Function, Sleep Medicine

Ratih Pahlesia,1 Faisal Yunus,1 Budhi Antariksa,1 Ratnawati,1 Dody Widodo1
1Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta
2Departemen THT Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta

Background: Patients with COPD may have a concomitant sleep apnea that can further exacerbate their gas exchange during sleep. They have an increased risk of developing hypercapnic respiratory insufficiency, nocturnal hypoxemia and pulmonary hypertension. If they remain undiagnosed and untreated will lead to complications such as cor pulmonale, respiratory failure, hypertension, coronary disease, congestive heart failure, stroke, cognitive impairment, loss of productivity in the work, and the increased risk of vehicle accidents. The aim of this study was to know the prevalence of OSA in stable COPD patients with mild to severe degree.
Methods: In observational cross sectional study, sixty-eight stable COPD patient in Persahabatan Hospital Jakarta on June 2010 with mild to severe degree were admitted to the study and interviewed using the Berlin questionnaire. Patients who have a high risk of sleep apnea will proceed with the examination of polysomnography to detect the presence of OSA. Last ENT examination to determine the anatomical defects suffered by these patients.
Results: There were 17 (25%) of 68 COPD patients who have a risk for the occurrence of OSA, while based on polysomnography examination in 17 patients found 5 patients (31,25%) or 7,35% of the 68 research subjects who suffer from OSA. Weight, BMI and neck circumference as risk factors for OSA, but only neck circumference was statistically significant as a risk factor for OSA. There were no correlation between stage of COPD, history of smoking, and degree of OSA.
Conclusion: Study found that the prevalence of OSA in patient with mild to severe COPD is 7,35% and neck circumference is a risk factor for OSA. (J Respir Indo. 2016; 36: 182-91)

Keywords: COPD, obstructive sleep apnea, Berlin quesionaire, polysomnography

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