Tag archives for HDAC2

Levels of HDAC2 and SGRQ-C in C and D Grup COPD Patients with Inhaled ICS/LABA and History of Smoking

Triwahju Astuti, Ungky Agus Setyawan, Sri Handayani Rahayu Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Brawijaya, Malang Abstract Background: In chronic obstructive pulmonary disease (COPD,) especially in smoker patients, there is a reduction in histone deacetylase-2 (HDAC2) activity and expression which is caused by oxidative stress. It’s linked with corticosteroids resistance. GOLD recommendation therapy […]