Tag archives for NSCLC

Expression of Protein Telomerase on Paraffin Block Preparations of Non-Small Cell Lung Cancer

Heidy Agustin1, Elisna Syahruddin1, Faisal Yunus1, Endarjo S2 1Departemen Pulmonologi dan Kedokteran Respirasi Fakultas Kedokteran Universitas Indonesia, RSUP Persahabatan, Jakarta 2Departemen Patologi Anatomi, RSUP Persahabatan, Jakarta Abstract Background: Lung cancer is a leading cause of death from cancer group. Prooncogenes and tumor suppressor genes role are separately known as k-ras, p53 and myc. Other factors […]

Efficacy and Toxicity Chemotherapy with Cisplatin + Etoposide Regiment in Advanced Stage Non-Small Cell Lung Cancer

Syahruddin E, Marlina N, Hudoyo A. J Respir Indones. 2012;32(1):25-35. Abstract Introduction: Standard chemotherapy for non-small cell lung cancer is platinum based regiment. Cisplatin is one the most potent anti-cancer agent that widely used for lung cancer. Meta-analysis results shows cisplatin has efficacy superior than carboplatin. In our experient, carboplatin based more often used in […]

Neurological Clinical Symptoms and CT Scan Brain Images of Lung Cancer Patients Small Cell Carcinoma is Not Brain Metastasis In Persahabatan Hospital

Yulianti D, Syahruddin E, Hudoyo A, Icksan A. J Respir Indones. 2011;31(1):32-7. Background. Brain is one of the common sites of distant metastasis in patients of lung cancer, and incidens of brain metastasis in lung cancer is considered high. In Non-small Cell lung cancer guide line, brain CT done if the neurological symptoms occured. Therefore […]

Expression Protein p53 mutation in Non-Small-Cell Lung Carcinoma

Hanafi AR, Syahruddin E, Hudoyo A, Hidayat H, Suzanna E. J Respir Indones. 2010;30(3):134-45 Introduction. The tumor suppressor gen p53 mutation encodes a protein that inhibits programmed cell death (apoptosis). The protein is expressed in basal cells in normal human epithelium, but no data are available on the frequency or clinical importance of its expression […]

Respons Dan Toleransi Pasien Adenokarsinoma Paru Stage III Dan IV Untuk Pemberian Kemoterapi Dengan Rejimen Paclitaxel (Paxus®) Plus Carboplatin

Syahruddin E, Hudoyo A, Jusuf A. J Respir Indones. 2010;30(2):105-111. Purpose: Combined new agents (paclitixel, gemcitabine and docetaxel) with platinum based were used as standard chemotherapy for non-small cell lung cancer. Meta analysis study that four regimen have similar efficacy, such as paclitaxel and cisplatin. Paxus® is a new paclitaxel derived from Taxus chinesis plant […]

Ekspresi Protein Bcl-2 pada Sediaan Blok Parafin Jaringan Kanker Paru

Marleen FS, Syahruddin E, Hudoyo A, Endarjo S, Hidayat H, Suzanna E. J Respir Indones. 2009;29(4). Background: Apoptosis plays a key role in the development of malignant tumors. The Bcl-2 oncoprotein is known to promote cell survival that inhibits programmed cell death (apoptosis). The Bcl-2 family of proteins either pro-apoptotic or anti-apoptotic functions might play […]

Ekspresi Sitokeratin 19 Dari Bilasan Bronkus Penderita Kanker Paru Jenis Karsinoma Bukan Sel Kecil dan Penderita Risiko Tinggi Kanker Paru Dengan Metode Imunohistokimia

Putra NPP, Muktiati NS, Mulyartha K, Siswanto. J Respir Indones. 2009;29(4). Background: Nowadays, in industrialized countries, lung cancers the most frequent cancer in men. Lung cancers also one of several malignancy in women. Lung cancer is one of several lung disease that need to be handled and managed fast and appropriately. Complicated skill and facility […]